In terms of taking on lots of enemies at once - like the sociopathic killing machine you've turned into.

I like exterminating the Talon Company - seeing they put so much effort in turning up when I least expect to try to assassinate my character. Bastards

Lately I've started to treat them as mobile body armour delivery systems as my current character can't wear power armour

Raiders, its fun to quick travel to places where there are lots of them get into vats and kill them all without them scratching you (grim reapers spirit is the bestest )

I love walking out of a building , where the try to ambush you , i just run up and blow them apart with my lil friend Mr shotgun

Moira, that bitch.

OH HOW ARE THOSE HOT LITTLE POTATOES